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Alzheimer Disease Biomarkers, Attentional Control and Semantic Memory Retrieval: Synergistic and Mediational Effects of Biomarkers on a Sensitive Cognitive Measure

About the Course:

Considerable research has focused on cognitive performance characteristics which can best discriminate healthy aging from the earliest stages of Alzheimer disease. Of increasing importance is the identification of potential biomarkers that may help facilitate early detection of the disease. This study examined the utility of combining attentional control with semantic retrieval as a sensitive correlate of such biomarkers and used mediation analyses to examine possible mechanisms by which identified Alzheimer disease biomarkers influence cognition.

Publication Date:

Neuropsychology, 29(3) 2015

Course Material Authors

Andrew Aschenbrenner, PhD

Dr. Aschenbrenner is an Instructor of Neurology at Washington University in St. Louis School of Medicine. His work focuses on cognitive changes that occur in healthy aging, preclinical Alzheimer disease and very mild dementia of the Alzheimer type. He has published multiple articles and presented at several conferences.

David Balota, PhD

Dr. Balota is a Professor of Psychological & Brain Sciences and Neurology at Washington University in St. Louis. Professor Balota works on issues related to visual word recognition, semantic memory, priming on implicit memory tests, and attention systems that modulate performance within each of these domains. He investigates these phenomena within young adults, older adults, and individuals who have dementing illnesses such as senile dementia of the Alzheimer’s type. He has published multiple articles in this area.

Recommended For:

This course is recommended for health care professionals, especially psychologists, counselors, social workers, and addiction counselors who seek knowledge about Alzheimer’s disease. This content is at the advanced level and this course is appropriate for participants with intermediate or advanced levvel of knowledge.

Course Objectives:

  1. Identify at least three of the biomarkers for the prodromal stage of Alzheimer’s disease.

  2. Describe at least 2 of the biomarkers associated with cognitive changes secondary to Alzheimer’s disease.

  3. Identify 2 neuropsychological instruments useful in measuring cognitive functioning.

  4. Discuss the salient results from this study.

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Course Material

Exam Questions

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Course Number 102314
2 credit hours
  • Online Article
Exam Fee: $13.94No exam fee with a Plus or Unlimited membership package!
4.2 out of 5
29 members have taken this course